Complete Whey Isolate Matrix: All 51 Products Compared (2026)
All 51 whey isolates in our catalog, side by side. Isolates run 90%+ protein content with lactose stripped out, making them the go-to choice for lactose-sensitive lifters and anyone cutting strictly on protein and water. This matrix shows the Value Score, macros, and price floor for every isolate we track so you can pick the right one for your wallet and your stomach.
How to Read This Matrix
Twelve columns, one row per product. The columns are: rank by Value Score, brand (links to the brand page), product name (links to the full live-price page), flavor, tub size in pounds, grams of protein per serving, total servings in the tub, calories per serving, cheapest in-stock price across our 12 tracked US retailers, the retailer at that price, the Value Score (0-100, higher is better), and short notes calling out the most relevant detail like grass-fed, hydrolyzed, or organic.
Why whey isolate matters
Isolate is filtered further than concentrate. The result is more protein per scoop (typically 25-30g vs 20-24g for concentrate), almost no lactose, and a higher price tag. The matrix below lets you spot the value plays: a few brands have closed the gap to concentrate prices while keeping the macro profile premium.
The Matrix
Sorted by Value Score, highest first. Every product name links to its full live-price page. Every brand links to the brand page. Scroll horizontally if you are on mobile.
| # | Brand | Product | Flavor | Size (lb) | Protein / serv | Servings | Calories / serv | Cheapest | Retailer | Value Score | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Nutricost | Whey Protein Isolate | Cookies & Cream | 5 lb | 30g | 67 | 135 | $62.95 | Walmart | 78 | Isolate |
| 2 | Nutricost | Whey Protein Isolate | Vanilla | 2 lb | 30g | 27 | 135 | $28.95 | Walmart | 60 | Isolate |
| 3 | Nutricost | Whey Protein Isolate | Chocolate | 5 lb | 25g | 72 | 115 | $41.99 | Amazon | 50 | Isolate |
| 4 | Nutricost | Whey Protein Isolate | Vanilla | 5 lb | 25g | 72 | 115 | $41.99 | Amazon | 50 | Isolate |
| 5 | Promix Nutrition | Grass-Fed Whey Isolate | Vanilla Bean | 5 lb | 25g | 74 | 115 | $99.99 | Amazon | 50 | Isolate, Grass-fed |
| 6 | Rule 1 Proteins | R1 Whey Isolate | Chocolate Fudge | 5 lb | 25g | 75 | 115 | $49.99 | Amazon | 43 | Isolate |
| 7 | MyProtein | Impact Whey Isolate | Chocolate Smooth | 5.5 lb | 25g | 79 | 115 | $54.99 | MyProtein | 42 | Isolate |
| 8 | Transparent Labs | 100% Whey Protein Isolate | French Vanilla | 5 lb | 28g | 76 | 127 | $59.99 | Transparent Labs | 41 | Isolate |
| 9 | Transparent Labs | 100% Whey Protein Isolate | Chocolate Peanut Butter | 5 lb | 28g | 76 | 127 | $59.99 | Transparent Labs | 41 | Isolate |
| 10 | Kaged | Whey Protein Isolate | Vanilla | 3 lb | 25g | 45 | 115 | $54.99 | Amazon | 40 | Isolate |
| 11 | Sports Research | Whey Protein Isolate | Vanilla Bean | 2 lb | 25g | 30 | 115 | $36.99 | Costco | 39 | Isolate |
| 12 | Sports Research | Whey Protein Isolate | Dutch Chocolate | 2 lb | 25g | 30 | 115 | $37.99 | Costco | 38 | Isolate |
| 13 | Rule 1 Proteins | R1 Protein Whey Isolate | Strawberries & Crème | 5 lb | 25g | 76 | 115 | $64.99 | Amazon | 38 | Isolate |
| 14 | Transparent Labs | 100% Grass-Fed Whey Protein Isolate | Cinnamon French Toast | 5 lb | 28g | 60 | 127 | $59.99 | Transparent Labs | 36 | Isolate, Grass-fed |
| 15 | Dymatize | ISO100 Hydrolyzed Whey | Birthday Cake | 5 lb | 25g | 75 | 115 | $59.99 | Amazon | 33 | Isolate, Hydrolyzed |
| 16 | Cellucor | Whey Sport Protein Isolate | Chocolate | 5 lb | 30g | 67 | 135 | $69.99 | Amazon | 33 | Isolate |
| 17 | Isopure | Zero Carb Whey Isolate | Creamy Vanilla | 7.5 lb | 25g | 103 | 115 | $89.99 | Costco | 33 | Isolate, Lactose-free |
| 18 | Kaged | Re-Kaged Whey Protein Isolate | Chocolate | 1.85 lb | 28g | 20 | 127 | $44.99 | Amazon | 32 | Isolate |
| 19 | Dymatize | ISO100 Hydrolyzed Whey | Gourmet Chocolate | 5 lb | 25g | 71 | 115 | $64.99 | iHerb | 32 | Isolate, Hydrolyzed |
| 20 | Promix Nutrition | Grass-Fed Whey Isolate | Dutch Chocolate | 2 lb | 25g | 30 | 115 | $49.99 | Amazon | 30 | Isolate, Grass-fed |
| 21 | Dymatize | ISO100 Hydrolyzed Whey Isolate | Chocolate Coconut | 5 lb | 25g | 71 | 115 | $79.99 | Amazon | 30 | Isolate, Hydrolyzed |
| 22 | Dymatize | ISO100 Hydrolyzed Whey | Gourmet Vanilla | 5 lb | 25g | 76 | 115 | $74.99 | Amazon | 29 | Isolate, Hydrolyzed |
| 23 | Dymatize | ISO100 Hydrolyzed Whey | Cookies & Cream | 5 lb | 25g | 74 | 115 | $74.99 | Amazon | 29 | Isolate, Hydrolyzed |
| 24 | Dymatize | ISO100 Hydrolyzed Whey | Peanut Butter | 5 lb | 25g | 71 | 115 | $74.99 | Amazon | 29 | Isolate, Hydrolyzed |
| 25 | Dymatize | ISO100 Hydrolyzed Whey | Strawberry | 5 lb | 25g | 76 | 115 | $74.99 | Amazon | 29 | Isolate, Hydrolyzed |
| 26 | Dymatize | ISO100 Hydrolyzed Whey | Fruity Pebbles | 5 lb | 25g | 71 | 115 | $76.99 | Amazon | 28 | Isolate, Hydrolyzed |
| 27 | Dymatize | ISO100 Hydrolyzed Whey | Cinnamon Bun | 5 lb | 25g | 71 | 115 | $76.99 | Amazon | 28 | Isolate, Hydrolyzed |
| 28 | Ascent | Native Fuel Whey Isolate | Vanilla Bean | 4 lb | 25g | 56 | 115 | $59.99 | Amazon | 27 | Isolate, Native whey |
| 29 | Ascent | Native Fuel Whey Isolate | Chocolate Peanut Butter | 4 lb | 25g | 56 | 115 | $59.99 | Amazon | 27 | Isolate, Native whey |
| 30 | Isopure | Zero Carb Whey Isolate | Alpine Punch | 3 lb | 25g | 41 | 115 | $44.99 | iHerb | 26 | Isolate, Lactose-free |
| 31 | Isopure | Zero Carb Whey Isolate | Dutch Chocolate | 3 lb | 25g | 41 | 115 | $44.99 | iHerb | 26 | Isolate, Lactose-free |
| 32 | Dymatize | ISO100 Hydrolyzed Whey | Gourmet Chocolate | 3 lb | 25g | 44 | 115 | $47.99 | Amazon | 26 | Isolate, Hydrolyzed |
| 33 | Animal | Animal Whey Isolate Blend | Chocolate | 4 lb | 25g | 53 | 115 | $59.99 | Amazon | 26 | Isolate |
| 34 | Animal | Animal Whey Isolate Blend | Vanilla | 4 lb | 25g | 53 | 115 | $59.99 | Amazon | 26 | Isolate |
| 35 | ProSupps | PS Whey Isolate | Chocolate Milkshake | 2 lb | 25g | 30 | 115 | $39.99 | Amazon | 25 | Isolate |
| 36 | Animal | Animal Whey Isolate Blend | Cookies & Cream | 4 lb | 25g | 53 | 115 | $61.99 | Amazon | 25 | Isolate |
| 37 | Klean Athlete | Klean Isolate | Chocolate Milkshake | 1.31 lb | 20g | 20 | 95 | $43.95 | Vitacost | 24 | Isolate |
| 38 | Klean Athlete | Klean Isolate | Natural Vanilla | 1.3 lb | 20g | 20 | 95 | $43.95 | Vitacost | 24 | Isolate |
| 39 | Kaged | Whey Protein Isolate | Chocolate | 5 lb | 25g | 75 | 115 | $79.99 | Amazon | 24 | Isolate |
| 40 | Klean Athlete | Klean Isolate | Natural Strawberry | 1.3 lb | 20g | 20 | 95 | $43.95 | Vitacost | 23 | Isolate |
| 41 | Animal | Animal Whey Isolate Blend | Vanilla | 2 lb | 25g | 27 | 115 | $34.99 | Amazon | 22 | Isolate |
| 42 | Animal | Animal Whey Isolate Blend | Chocolate | 2 lb | 25g | 27 | 115 | $34.99 | Amazon | 22 | Isolate |
| 43 | Dymatize | ISO100 Hydrolyzed Whey Isolate | Strawberry Smoothie | 1.6 lb | 25g | 24 | 115 | $36.99 | Amazon | 22 | Isolate, Hydrolyzed |
| 44 | Quest Nutrition | Quest Multi-Purpose Protein Powder | Coffee Toffee | 2 lb | 22g | 30 | 103 | $42.99 | Amazon | 22 | Isolate |
| 45 | Quest Nutrition | Quest Multi-Purpose Protein Powder | Salted Caramel | 2 lb | 22g | 30 | 103 | $42.99 | Amazon | 22 | Isolate |
| 46 | Legion Athletics | Whey+ Whey Isolate | Salted Caramel | 2.2 lb | 22g | 30 | 103 | $49.99 | Amazon | 22 | Isolate |
| 47 | Transparent Labs | 100% Grass-Fed Whey Protein Isolate | Mint Chocolate Chip | 2.5 lb | 28g | 30 | 127 | $59.99 | Transparent Labs | 22 | Isolate, Grass-fed |
| 48 | Optimum Nutrition | Platinum Hydrowhey | Turbo Chocolate | 3.5 lb | 30g | 41 | 135 | $64.99 | Amazon | 22 | Isolate |
| 49 | Kaged | Re-Kaged Whey Protein Isolate | Vanilla | 4 lb | 28g | 43 | 127 | $69.99 | Amazon | 18 | Isolate |
| 50 | Legion Athletics | Whey+ Isolate Protein | Chocolate Peanut Butter | 2.2 lb | 22g | 30 | 103 | $44.99 | Amazon | 17 | Isolate |
| 51 | Legion Athletics | Whey+ Isolate Protein | French Vanilla | 2.2 lb | 22g | 30 | 103 | $44.99 | Amazon | 17 | Isolate |
Top 5 Winners by Different Metrics
The single Value Score column is the right place to start, but it is not the only way to slice this matrix. Here are five different angles on the same product set:
How We Built This Matrix
Every row above is generated directly from our live product catalog. When the scraper checks each retailer (every two hours throughout the day), the cheapest in-stock price wins the right-hand column. Value Score is recalculated whenever a price changes. We do not score products that are out of stock at every retailer.
To learn more about how the Value Score combines price per gram with retailer reliability, label-claim accuracy, and third-party testing, read how it works and our editorial standards. The methodology is the same across every matrix on this site.
FAQ
How many whey isolate products does this matrix cover?
This matrix covers 51 whey isolate products from 17 different brands. It is a complete view of every product in this category that we currently track. New products are added as our scrapers find them and old products are removed when they go permanently out of stock.
How often is this matrix updated?
Prices are refreshed automatically every two hours across all 12 retailers we track. Value Score, ranking order, and the cheapest-retailer column update whenever a tracked price changes. You can see live scraper health at /scraper-status/.
Why is the cheapest product not always the highest Value Score?
Value Score combines price per gram of protein with retailer reliability, label-claim accuracy from third-party testing, and customer-reported flavor and mixability. A very cheap tub from a brand with a recall history or thin label disclosure can lose to a slightly more expensive tub from a brand that tests every batch. Read the full methodology at /how-it-works/.
Can I sort the matrix by a different column?
Not yet on this page. We rank by Value Score because that single number rolls in the most decision-relevant factors. If you want to sort by raw price, protein per dollar, or pack size, the /best-value/ live rankings page lets you filter and sort across every category.
Is whey isolate worth the price premium over concentrate?
If you are lactose-sensitive, yes: isolate is filtered to under 1% lactose versus concentrate's 4-8%. For everyone else, it is a quality-of-life upgrade rather than a strict necessity. Isolate mixes thinner, tastes cleaner, and packs more protein into a smaller scoop. Compare costs with our concentrate matrix at /matrix/whey-concentrate-matrix/.
Where can I see live retailer prices for any product in this matrix?
Every product name in the matrix links to its full live-price page. On that page you will see all 12 retailers we track, their current in-stock prices, a price history sparkline, and a Value Score breakdown. You can also browse the full whey isolate category at /whey-isolate/.
See live whey isolate rankings
Filter by brand, retailer, size, and Value Score on the full category page.
Browse Whey Isolate →